Major Depressive Disorder

Medically reviewed by Sample Data Updated August 2026

Overview


Major depressive disorder is a mood disorder causing persistent feelings of sadness and loss of interest.

Symptoms of Major Depressive Disorder


Low mood, fatigue, changes in appetite or sleep, and difficulty concentrating.

What Causes Major Depressive Disorder?


Thought to involve a combination of genetic, biological, and environmental factors.

How is Major Depressive Disorder Diagnosed?


Diagnosed by a healthcare provider based on symptoms present for at least two weeks.

Treatment for Major Depressive Disorder


Psychotherapy, medication, or a combination of both are commonly used.

How to Prevent Major Depressive Disorder


Maintaining social connections and healthy routines may help lower risk of recurrence.
1 Source

Mfamasia's health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date health standards.

  1. National Institute of Mental Health